The Breast Unit Perugia (S.S.Dip. Breast Unit) is an initiative of Perugia University together with the Azienda Ospedaliera di Perugia. At the moment it represents the main breast cancer center in Umbria. Each week we have a multidisciplinary meeting for case management. We offer a service based on breast conserving surgery, nipple sparing mastectomy with immediate reconstruction, axillary staging with sentinel node biopsy, PBI. Reserch and teaching activities are part of our mission. Gene Expression Tests are performed.