The Breast Clinic of the Portuguese Institute of Oncology of Porto is an integrated multidisciplinary unit of a comprehensive cancer center. The Breast Clinic follows the recommendations of the European Society of Mastology (EUSOMA)in order to offer high quality standards in breast cancer care. It is dedicated to clinical, research and teaching activities in the area of breast cancer. The Clinic offers a multidisciplinary approach including the early diagnosis, primary tumor local treatment, breast conservative surgery, sentinel node biopsy, breast reconstruction, systemic therapy, radiotherapy, risk assessment and genetic counselling, treatment of advanced disease and palliative care.